Will Knechtle, MBA, MPH
Will Knechtle, MBA, MPH
Innovations Program Manager - Duke Health
Will Knechtle works at the intersection of quality improvement, innovation, and clinical operations. At the Duke Institute for Health Innovation (DIHI), he manages AI implementation projects that directly impact hospital care quality, patient flow, and workforce burden. With experience spanning global public health, health systems strategy, and advanced analytics, Will brings both frontline empathy and system-level insight. He’s led multidisciplinary teams—including clinicians, data scientists, and administrators—to deploy machine learning and generative AI tools within real-world hospital workflows. His background in public health, biostatistics, and business (via Duke’s MPH and MBA programs) equips him to translate complex technology into tangible improvements in care. Will’s work bridges institutional goals with emerging tools, making him a compelling voice for quality leaders navigating the promise and pitfalls of AI.
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Will Knechtle, MBA, MPH

